Omeprazole was better than cisapride or placebo for controlling heartburn at 4 and 8 weeks
نویسندگان
چکیده
منابع مشابه
Heartburn treatment in primary care: randomised, double blind study for 8 weeks.
OBJECTIVE To compare the effects and tolerability of omeprazole and cisapride with that of placebo for control of heartburn in primary care patients. DESIGN Randomised, double blind, placebo controlled study. SETTING 65 primary care practices in Norway. PARTICIPANTS 483 untreated patients with complaints of heartburn >/=3 days a week, with at most grade 1 reflux oesophagitis. INTERVENTI...
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P a t i e n t s 3510 patients who were ≥ 18 years of age (mean age 47 y, 57% men), had endoscopically confirmed erosive esophagitis ≥ grade 2, and had had ≥ 1 episode of moderate-tovery-severe heartburn during the previous 3 days or nights, or both. Exclusion criteria included duodenal or gastric ulcers ≥ 3 mm in diameter; systemic disease affecting the esophagus; history of gastrointestinal bl...
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M e t h o d s Design: Randomized placebo-controlled trial. Allocation: Concealed.* Blinding: Blinded (patients and caregivers, clinicians, outcome assessors, and {data monitoring committee}†).* Follow-up period: 12 weeks. Setting: 8 clinical centers in England, United Kingdom. Patients: 259 patients > 39 years of age (mean age 85 y, 85% women) who had probable or possible Alzheimer disease (on ...
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ژورنال
عنوان ژورنال: Evidence-Based Medicine
سال: 2000
ISSN: 1356-5524
DOI: 10.1136/ebm.5.2.59